High C-reactive protein instead of metabolic syndrome is associated with lower bioimpedance phase angle in individuals clinically screened for a lifestyle modification program

BACKGROUND: Phase angle (PhA) value is a useful tool for identifying cell membrane integrity dysfunction. It is known that metabolic syndrome (MetS) increases oxidative stress and inflammation; and consequently can promote cellular damage. We hypothesized that MetS and inflammatory blood markers could be associated with lower PhA values. Therefore, the aim of this study was to identify the association of PhA values with MetS and blood markers in individuals clinically screened for a lifestyle modification program. METHODS: In a cross-sectional study, 417 selected subjects (76 men and 341 women, 53.9 ± 9.4 years old) were evaluated. Assessments included clinics, anthropometric measures, body composition by bioimpedance, and laboratory blood markers, including plasma lipids, glucose, and C-reactive protein concentrations. According to the PhA median values, subjects were classified in low (≤6.3°) and high (>6.3°) PhA groups. RESULTS: Subjects with lower PhA values were older and showed lower body mass index, waist circumference, muscle mass index, creatinine, and uric acid; and higher gamma-GT and HDL cholesterol. Neither the presence of MetS nor the presence of the increasing number of MetS components was associated with PhA values. The logistic regression analysis adjusted for age, gender, body mass index, and muscle mass index showed that higherC-reactive protein concentrations (>3.0 mg/L) increased the odds of low PhA values (OR = 1.62; CI = 1.01­2.60).CONCLUSION: Higher C-reactive protein concentrations increased the odds of low PhA independently of the presence of MetS. Additionally, contrary to our hypothesis, MetS was not associated with PhA values.

Association of dyslipidemia with intakes of fruit and vegetables and the body fat content of adults clinically selected for a lifestyle modification program / Associación de la dislipidemia con la ingestión de frutas y vegetales y el contenido de grasa corporal de adultos seleccionados para un programa de modificación del estilo de vida

To investigate the relationship of dyslipidemia with demographic distribution and patterns of body fat and dietary intakes. From a universe of adults clinically selected for a lifestyle modification program 979 subjects (409 males and 570 females, 52.2 ± 9.6 years) fulfilled the inclusion criteria. Overnight-fasting plasma was assayed (dry chemistry) for triglycerides (TG), total (TC) and HDL fraction of cholesterol given the non-HDL (n-HDL) fraction by the difference. Anthropometric assessment included body weight (kg), height (m), fat (bioelectrical impedance) and waist circumference (WC). Food intake was assessed by the 24-hour recall questionnaire and the food groups evaluated through recommendations from an adapted food pyramid. The chances of dyslipidemia from other variable changes were determined by logistic regression with p2 servings). Dietary intakes have protective effects against hypertriglyceridemia with whole grains, odds ratio (OR) 0.342 (CI 95%, 0.154-0.760), fruits >3 servings (OR 0.523, 0.290-0.941) and vegetables >4 servings (OR 0.360, 0.176-0.735). In general total body and abdominal adiposity influenced all dyslipidemia markers while dietary intake of fruits and vegetables protected against triglyceridemia.

Investigar las relaciones de dislipidemia con distribución demográfica y patrones de masa corporal e ingestión de alimentos. De un universo de adultos clínicamente seleccionados para un programa de modificación de estilo de vida, 979 sujetos (409 hombres y 570 mujeres, 52,2 ± 9,6 años) cumplieron con los criterios de inclusión. Se examinó el plasma cosechado tras ayuno nocturno (química seca) para averiguar si hay la presencia de triglicéridos (TG), colesterol total (CT) y fracción de colesterol dada la fracción no HDL por diferencia. Una evaluación antropométrica incluyó peso corporal (kg), altura (m), grasa (impedancia bioeléctrica) y circunferencia de la cintura (CC). Se evaluó la ingestión de alimentos con el cuestionario de tipo recordatorio de 24 horas y los grupos de alimentos evaluados por la pirámide de alimentos recomendada. Se determinaron las probabilidades de dislipidemia de otros cambios variables con regresión logística p2 porciones). El consumo en la dieta protege de hipertrigliceridemia con odds ratio de granos integrales (OR) 0,342 (CI 95%, 0,154-0,760), frutas >3 porciones (OR 0.523, 0.290-0.941) y hortalizas >4 porciones (OR 0.360, 0.176-0.735). En general la adiposidad corporal total y abdominal influenció todos los marcadores de dislipidemia y solamente la trigliceridemia fue protegida por ingestión de frutas y hortalizas en la dieta.